The treatment of acute rheumatic fever Biology essay
Acute rheumatic fever ARF: syndromic immunological non-suppurative sequelae of group A streptococci, GAS pharyngitis. In the US, the attack rate is now likely to drop by more than 0.4, after GAS, Cause. Acute rheumatic fever is a delayed consequence of pharyngitis and skin infections, such as impetigo, due to Streptococcus pyogenes. These bacteria are also called group A Streptococcus group A streptococcal bacteria. Streptococcal pharyngitis or skin infection usually precedes the onset of acute rheumatic fever by weeks. Acute rheumatic fever ARF is a non-purulent sequela that occurs two to four weeks after group A Streptococcus GAS pharyngitis and may include arthritis, carditis, chorea, erythema marginatum, and subcutaneous nodules. Damage to heart valves can be chronic and progressive, resulting in cardiac decompensation. Group A streptococcal GAS is the most common cause of bacterial pharyngitis in school-age children. The post-infection sequel, with acute rheumatic fever, ARF and rheumatic heart diseases, which cause morbidity and mortality among young people, are public health concerns in several developing countries. Asymptomatic transport, abstract. Rheumatic fever is one of the most neglected conditions and its pathogenesis remains poorly understood. Most of the research focuses on cross-reactivity between. Rheumatic fever is an inflammatory disease that occurs after a streptococcal throat infection, usually - It often affects the heart, joints, skin and brain in children -15. The biggest risk is permanent heart damage, known as rheumatic heart disease. Treatment includes antibiotics to eliminate streptococcal bacteria, anti. Etiology: Acute rheumatic fever ARF is a systemic inflammatory disease that occurs - after a group A streptococcal infection. ARF is mediated by an autoimmune response to antigenic components of the organism that cross-react with similar epitopes in the heart, joints, brain, and skin. Presentation: ARF is characterized by severe, acute rheumatic fever can be diagnosed based on the revised Jones for the diagnosis of ARF. Histologically, acute rheumatic valvulitis manifests with active inflammation characterized by lymphocytic infiltration, Aschoff bodies, and Anitschkow cells. Introduction. Rheumatic fever RF, or acute rheumatic fever ARF, is an autoimmune complication caused by the human-specific bacterial pathogen group A B-hemolytic streptococcal GAS, Streptococcus pyogenes. S. pyogenes is a Gram-positive aerobic bacterium that is coccoid or spherical in shape and usually occurs in pairs. Rheumatic heart disease RHD is an acquired, chronic autoimmune inflammatory valvular heart disease that causes heart disease. failure and premature death. 1 RHD is a consequence of a.