Sweet&Rsquo;S Syndrome and Subsequently Pyoderma Gangrenosum in a Patient with Chronic Hepatitis C Infection essay
Pyoderma gangrenosum: combination therapy with excellent results in a patient with underlying hepatitis C BMJ Case Rep. 2017, 2017:bcr2017223113. doi: 10.1136 bcr-2017-223113. Purpose of review To summarize the recent literature on the pathophysiology, diagnosis and treatment of pyoderma gangrenosum. Recent findings A complex interplay between both the innate and adaptive immune systems underlies the pathogenesis of pyoderma gangrenosum PG. The diagnosis remains a challenge as Pyoderma gangrenosum PG is a rare inflammatory neutrophilic disorder with prototypical clinical presentations. Its pathophysiology is complex and not fully explained. Recent information on the genetic basis of PG and the role of autoinflammation provides a better understanding of the disease and the new therapeutic Sweet's syndrome, the namesake for acute febrile neutrophilic dermatosis, is characterized by a constellation of clinical symptoms, physical features and pathological findings including fever, neutrophilia, tender erythematous skin lesions, papules, nodules and plaques, and a diffuse infiltrate consisting mainly of mature Pyoderma gangrenosum pg is a rare neutrophilic dermatosis characterized by painful necrotic ulceration that preferentially affects the lower extremities. The diagnosis is challenging, and a thorough investigation, including biopsy, is required. In this case report, we describe a year-old patient with a diagnosis of,