Stem cell transplantation in children and adolescents Biology essay
Embryonic stem cells have been used for research in the past, but ethical concerns have led to their being largely replaced by stem cells derived from other sources. Tissues from which adult oligopotent and unipotent stem cells are isolated include bone marrow, adipose tissue, and trabecular bone. has bone marrow, Background: Adolescent and young adult AYAs with acute lymphocytic leukemia are ALL treated with various chemotherapy regimens. Some patients undergo allogeneic hematopoietic stem cell transplantation (HCT) due to genetic features of high-risk, chemoresistant disease that fails to achieve measurable residuals in a timely manner. The prognosis of acute lymphocytic leukemia in children has improved dramatically, and recent studies have reported excellent results. survival rate now, for childhood ALL in general, prognosis remains poor in adolescent and young adult AYAs, 2,3. ALL commonly presents certain adverse AYAs in adolescents and young adults represent a challenging group of acute lymphocytic leukemia ALL patients with specific needs. Although there is increasing evidence from comparative studies that this age group benefits from intensified pediatric chemotherapy, the impact and optimal implementation of hematopoietic stem, A stem cell, found in embryonic stem cells from embryos, and somatic stem cells from adults is an immature, non- mature stem cell. -specialized cell that can differentiate into one or more specific functioning or regenerating cell types. This makes them useful in the treatment of degenerating diseases. A totipotent stem cell can become any cell type within the patient's descriptive analysis. The total number of children and adolescents undergoing allo-HCT for myelofibrosis MF was analyzed based on data reported to the EBMT.