Hepatoprotective and Antidiabetic Effect of Phyllanthus Extract Biology essay




The liver was immediately removed and part of it was fixed with formalin to study pathological changes. Thiobarbituric acid was used to analyze lipid peroxide levels in liver and serum. The extract of P. emblica was found to be hepatoprotective in both acute and chronic induced hepatotoxicity. Jose and Kuttan, 2000. 3.4. Cardio-protective. Meniran, Phyllanthus niruri Linn. is a herbal plant often used in medicine. Meniran extract contains antibacterial substances and can therefore be used to inhibit bacterial growth. Moreover, this extract also consists of bioactive compounds that have antibacterial activity of terpenoids, alkaloids, flavonoids, saponins and tannins. The toxicity effect of Chanca piedra, Phyllanthus niruri leaves extract was investigated on albino rats. Rats were divided into four groups, four per group. only received water and food. The plants of the genus lt i gt, Phyllanthus lt, i gt, Euphorbiaceae have long been used as traditional medicinal materials in China, India, Brazil and Southeast Asian countries. They can be used to treat digestive diseases, jaundice and kidney stone. This review discusses the ethnopharmacological, The genus Phyllanthus L. is one of the most important groups of plants belonging to the Phyllantaceae family. Phyllanthus urinaria L. is an annual perennial herb species found in tropical Asia, America, China and the islands of the Indian Ocean. P. urinaria is used in folk medicine as a remedy for jaundice, diabetes, malaria and liver. Liver fibrosis is a pathological variation caused by almost all chronic liver injuries. Phyllanthus emblica PE has been reported to be an edible and medicinal natural resource that possesses hepatoprotective, antioxidant and anti-inflammatory properties and may have a soothing effect on liver fibrosis. To investigate the protective effect, analgesic and antipyretic effects of ethanol and aqueous extracts of the plant in mice Perianayagam, et al, 2004, gastroprotective effects of ethanol extract of fruits in different experiments. Two partially purified organic fractions of the non-fat ethanol extract of aerial parts of Phyllanthus reticulatus showed promising hepatoprotective activity, as evidenced by significant changes in pentobarbital-induced sleep time, changes in serum levels of sGPT, sGOT, sALP and bilirubin and also by histopathological changes. as compared. PASS prediction test Lagunin et al. 2000, which is extensively studied today, is based on research mainly on structure-activity relationships of the training set, which generally contains more biological actions, which makes it interesting to estimate whether a phytochemical compound has,





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