The promise of personalized medicine Biology essay




Abstract. “Personalized medicine” is based on identifying and integrating individual variability in genomic, biological and physiological parameters, as well as in environmental and lifestyle factors, to define “individually” targeted disease prevention and treatment. Although innovative 'omic' technologies supported the application. To characterize differences in total N-glycan levels, serum samples from healthy control women were compared with those obtained from patients diagnosed with late-stage relapsed OC, and increased amounts of tri- and tetra-branched structures with varying degrees of sialylation were observed. and fucosylation measured. revealed in OC: It may be more useful to think of personalized medicine as the embodiment of a promise economy that serves both to mobilize resources for research and to define the ends to which that research is directed. Rather than trying to distinguish between hype and legitimate promise, it may be more useful to think about personalized medicine, as personalized medicine promises prediction, prevention and treatment of diseases tailored to the needs of the individual. New technologies for detailed biological profiling of individuals at the molecular level have been critical in initiating the transition to personalized medicine. Even more new technologies will be needed if the vision is that the rapid development of high-throughput technologies and computational frameworks will enable the investigation of biological processes. systems in unprecedented detail. The ability to study biological phenomena at the omics level is in turn expected to lead to significant advances in personalized and precision medicine.Claes Wahlestedt. Charles B. Nemeroff. BMC Medicine 2013 This review focuses first on the concept of pharmacogenomics and the related concepts of biomarkers and personalized prescribing. Next one. Bioinformatics in personalized. G. Sunil Krishnan, Amit Joshi and Vikas Kaushik. Abstract. Genomics provides targeted biological information because it is part of the life sciences. MRNA technologies have the potential to transform areas of medicine, including the prophylaxis of infectious diseases. The benefits for vaccines range from the acceleration of immunogen.





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