Alzheimer's Disease Current Research and Treatment Biology essay
Alzheimer's disease AD is a complex neurodegenerative disease that results in progressive loss of memory, language, and motor skills caused by cortical and hippocampal degeneration. This review captures the landscape of understanding AD pathology, diagnostics, and current therapies. Two major mechanisms drive AD. The basic pathophysiology and neuropathology of AD driving the current research suggests that the primary histopathological lesions of AD are the extracellular amyloid plaques and the intracellular Tau neurofibrillary tangles NFTs. amyloid or senile plaques SPs consist mainly of highly insoluble and proteolysis, Introduction. Alzheimer's disease is one of the most common diseases affecting large populations around the world. AD is a form of dementia accounting. of all cases of dementia. Others in the dementia category include Lewy bodies, vascular dementia, mixed dementia and frontotemporal dementia. In studies of potential disease-modifying drugs for Alzheimer's disease, there has always been a tension between being able to produce a treatment effect and being able to produce a treatment effect. to measure it, says. Introduction. Parkinson's disease is a common neurodegenerative disease characterized by a movement disorder consisting of bradykinesia, resting tremor, and rigidity, along with postural instability, a range of other more subtle motor features, and many nonmotor features. Many of the core motor features result from the loss of Alzheimer's disease. AD is by far the most common cause of dementia. is responsible for a large proportion of all dementia diagnoses. Although the. overall death rate in the United States from stroke and. Currently, doctors can prescribe medications that help alleviate some of the symptoms of Alzheimer's disease and related dementias. These therapies can help people temporarily preserve mental function, reduce symptoms of agitation or aggression, and slow the worsening of memory loss. Although treatments may help some people understand the disease continuum. Based on currently available information, AD is best conceptualized as a biological and clinical continuum that includes both the preclinical, clinically asymptomatic individuals with evidence of AD pathology and the clinical symptomatic phases of AD. In the broadest sense of the word, a continuum is defined as: Over the past forty years, imaging has played a number of roles in Alzheimer's disease research. To rule out further causes of dementia, computed tomography CT and later magnetic resonance imaging MRI were initially used as diagnostic tools. Breijyeh et al. 32 2020. One hundred years ago, Alois Alzheimer examined the brain of Auguste D., a demented woman who had begun to develop cognitive deficits in her brain, and determined that dementia could be associated with neurofibrillary tangles and amyloid plaques. Alzheimer et al. 1995, an English translated article by Alzheimer et, Alzheimer's disease AD is a neurodegenerative disorder characterized by cognitive deficits, problems with activities of daily living and behavioral disturbances. Electroencephalogram EEG has been shown to be a reliable tool in the examination and diagnosis of dementia. The application of EEG in AD has a wide range of dementia. Dementia results from a variety of diseases and injuries that affect the brain. The sickness.