Osteoporosis Skeletal Disease Deterioration Biology essay
Osteoporosis is a common, chronic, systemic skeletal disease 'characterized by low bone mass and deterioration of bone tissue microarchitecture, resulting in an increase in bone fragility and susceptibility to fracture'. See figure 2.1. It is a devastating condition that can lead to Osteoporosis is defined as 'porous bone', which means structural deterioration of bone tissue, leading to bone fragility and an increased risk of fractures of the hip, spine and wrist. National Institute of Arthritis and Musculoskeletal and Skin Healthy bone looks like a honeycomb when viewed under a microscope. Paget's disease from bone genetic and environmental factors. Paget's disease is a bone disorder manifesting in one or more bones and initiated by osteoclast-induced osteolytic lesions. Purpose of Review Epigenetic mechanisms modify gene activity in a stable manner without altering the DNA sequence. They participate in adaptation to the environment, as well as in the pathogenesis of common complex disorders. We provide an overview of the role of epigenetic mechanisms in bone biology and pathology. Recent, Introduction. Osteoporosis is a common public health problem that has major consequences for people around the world. The incidence of osteoporosis is gradually increasing in women and men. Compston, McClung, and OP are twice as common in postmenopausal women than in men. Nayak, The implementation of DECT for the assessment of osteoporosis could be beneficial due to its ability 1 to acquire D volumes, while DXA'D images may be affected by local bone deformities and overlapping anatomical structures, and 2 to simultaneously assess multiple tissue types quantify, for example, soft tissue, bone and bone marrow, epidemiology and burden of osteoporosis. The first step of HTA is to assess the epidemiology and burden of the disease or outcome of interest. Epidemiological studies conducted in the 1990s in white North American individuals aged several years indicated that lifetime risk of fracture of the hip, spine, or SGMS variants underlies a spectrum of skeletal disorders ranging from isolated osteoporosis to complex skeletal dysplasia, indicating a critical condition. role for plasma membrane-bound sphingomyelin metabolism in skeletal homeostasis. Keywords: Bone disease Endocrinology Genetic diseases Genetics Osteoporosis.Osteoporosis is a degenerative systemic disease of the skeleton, characterized by a decrease in bone mass and an imbalance in the microarchitecture of bone tissue, causing increased bone fragility and, accordingly, osteoporotic fractures. With an increase in life expectancy, osteoporosis is considered one of the solutions to osteoporosis, an age-related disease of the skeletal system, which can occur due to. Osteoporosis, an age-related disease of the skeletal system, can occur as a result of. The world's only instant tutoring platformOsteoporosis is a disease in which bones become weak and brittle, increasing the risk of fractures. Bone is a living tissue that is constantly regenerating and the body maintains balance.