Treatment of heart failure using stem cell therapy Biology essay




Heart cell therapy with adult stem cells. Cardiac cell transplantation was first described in the mid-1990s by several groups using different cell types. 70, 115 Directly transplanting cells into and around the damaged myocardium reduced scar formation and improved LV function after myocardial infarction. 70, 114 Cardiopoietic stem cell therapy for heart failure, the C-CURE study, is one of the first studies of its kind to be started on this principle. 19 Analysis after two years showed an improvement in the status of cardiovascular functioning with the help of such cells. Conventionally, cancer therapy is based on various pharmacological and radiation-based interventions, often through chemotherapy and radiotherapy. 1- Challenges in the clinical success of cancer therapy result from limitations in the interventional mechanisms themselves. Often this is due to the fact that the first LAPiS escalation study in humans uses cardiomyocytes differentiated in vitro from induced pluripotent stem cell iPSCs. The heart muscle cells are injected directly. Physician-scientists at the Texas Heart Institute today announced results from the largest cell therapy study to date in patients with chronic heart failure due to low ejection fraction. The therapy benefited patients by improving the heart's pumping ability, as measured by ejection fraction, and reducing the risk of heart attack or stroke. New cell therapy offers potential treatment option for patients with chronic heart failure. Houston, Texas – Physician-scientists at the Texas Heart Institute today announced results from the largest cell therapy trial to date in patients with chronic heart failure due to low ejection fraction. The therapy was helpful,





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