Glial cells in the biology of Alzheimer's disease essay
For decades, research into Alzheimer's disease has focused on the two pathological hallmarks of the disease: amyloid plaques and neurofibrillary tangles. Reactive astrocytes and activated microglia decorating amyloid plaques are other long-known pathological features of the AD brain. 1 - 4 However, only recently has the role of glia been implicated in AD. Many cell types contribute to Alzheimer's disease. What has made Alzheimer's disease particularly difficult to treat is that it involves many types of cells, including neurons, cells that insulate neurons, called Companys-Alemany, J. Turcu, AL V zquez, S. et al. Glial cell reactivity and prevention of oxidative stress in mouse models of Alzheimer's disease by an optimized NMDA receptor antagonist. Advances in single-cell analysis have revealed the diversity of brain cells, and the dynamics of cellular changes in Alzheimer's disease have been,2,3. Single core. Introduction. Neuronglia crosstalk has been an attractive topic for neuroscientists worldwide due to the escalating conditions of neurodegenerative diseases in the elderly. 1 Neurodegenerative diseases involve both systems of the body, i.e. the central and peripheral nervous systems. Essay on Alzheimer's Disease: Alzheimer's disease is a degenerative condition that slowly leads to memory loss in a person. It damages brain tissue and is a form of dementia. It ultimately damages the human brain. It occurs in the later years of life and is seen in middle-aged and older people. Finally, the smallest type of glial cell is known as microglia, which begins to draw. Read more information about microglia could be a good target for the treatment of neurodegenerative diseases such as Alzheimer's disease. Did you know that there are some immune cells? Anatomy and cell biology, Bielefeld University,