Rapid Bedside Diagnosis of Spontaneous Bacterial Peritonitis Biology Essay
Spontaneous bacterial peritonitis SBP requires prompt diagnosis before starting antibiotics. The diagnosis is usually based on manual examination of ascitic fluid AF with long-term reporting. Spontaneous bacterial peritonitis SBP is an ascites infection unique to patients with cirrhosis and associated with high mortality. In the English literature, the first descriptions of ascites infection in cirrhosis occurred in the mid-1960s. Serum procalcitonin could be used with a high degree of accuracy as an additional noninvasive biomarker in diagnosing SBP in cirrhotic patients. Addition of CRP does not appear to significantly increase the diagnostic accuracy of procalcitonin. Keywords: Procalcitonin, peritonitis, liver cirrhosis, C-reactive protein, Background: Spontaneous bacterial peritonitis SBP is a serious complication of cirrhosis and is associated with high morbidity and mortality. Prompt initiation of appropriate antibiotics is critical for improved patient outcomes. Properly obtaining ascites fluid for analysis results in several technical and logistical limitations, at a glance. Spontaneous bacterial peritonitis SBP, also called primary peritonitis, is an infection of the peritoneal cavity with no apparent intra-abdominal source. SBP must be that. Spontaneous bacterial peritonitis SBP is defined as an ascitic fluid infection without an obvious intra-abdominal, surgically treatable source. 1 The presence of SBP, which almost always occurs in patients with cirrhosis and ascites, is suspected because of signs and symptoms such as fever, pain or altered mental status, criteria for treatment. Individuals with suspected spontaneous bacterial peritonitis SBP and ascitic fluid PMN greater than or equal to cells, 0.25, L should receive immediate empiric antibiotic therapy. Furthermore, individuals with culture-negative neutrocytic ascites have similar mortality rates as individuals with culture-positive. In cirrhotic patients with spontaneous bacterial peritonitis treated with cefotaxime, resolution of the infection and patient survival can be predicted by several clinical and laboratory variables obtained at the time of treatment. infection diagnosis the most important are blood urea nitrogen level, serum aspartate aminotransferase level and site community, Abstract. Spontaneous bacterial peritonitis SBP is a common complication in patients with liver cirrhosis, with an increased risk of mortality. For this reason, a diagnostic paracentesis should be performed.