Bacterial Resistance to Antimicrobials Biology Essay
In addition to intrinsic resistance, bacteria can acquire resistance to certain antimicrobials through the transfer of genetic material that confers resistance. Among the most common strategies for bacterial resistance include: changes in drug target site, increased cell wall permeability to antibiotics, inactivation of antibiotics, and amoxicillin is a commonly used antimicrobial beta-lactam drug, approved by the US Food and Drug Administration (FDA) for use in primary healthcare. healthcare institution. Amoxicillin is an aminopenicillin that is produced by adding an extra amino group to penicillin to combat antibiotic resistance. This drug is indicated for the treatment of infections caused by sensitive. The optimism of the early period of antimicrobial discovery has been tempered by the emergence of bacterial strains resistant to these therapies. Today these are clinically important bacteria. The microbial ecology of the human mouth and gastrointestinal tract is very complex. The use of broad-spectrum antimicrobials can lead to i proliferation of previously minor components of the microbiota, ii colonization by saprophytic organisms, iii colonization by antimicrobial resistant pathogens, increasing the risk of. The effective use of an antimicrobial agent is undermined by the potential for tolerance or resistance that develops from the first use. This applies to antimicrobials used to treat bacterial, viral, fungal and parasitic infections. Various physiological and biochemical mechanisms can control this development. Antibiotic resistance is a global health problem, involving the transfer of bacteria and genes between people, animals and the environment. Although multiple barriers restrict the flow of both. Antibiotic-resistant bacteria are responsible for millions of difficult-to-treat infections every year. Since antibiotic “miracle drugs” were first introduced into clinical use, resistance has recently followed closely. This problem has been greatly exacerbated by its extensive use in medicine and agriculture, combined with its remarkable potency,