Drug design is an inventive essay on process biology
Due to recent advances in computing power and technology, computer-aided drug design CADD has become an integral part of modern drug discovery to guide and accelerate the process. In this review, we present an overview of the important CADD methods and applications, such as in silico structure prediction, A Structure-Based Drug Discovery Paradigm. This review focuses on currently available methods and algorithms for structure-based drug design, including virtual screening and de novo drug design, with special emphasis on AI and deep learning-based methods used for drug discovery. Expand.Medicinal chemistry faces new challenges in approaching precision medicine. Several powerful new tools or improvements on already used tools are now available to medicinal chemists to aid in drug discovery, from a hit molecule to a clinically used drug. Among the new instruments, the opportunity to consider Pharmatech means for us combining deep expertise in drug development with technology. At Exscientia, it's about how we use technology to accelerate drug discovery and development.